502 E Washington Street Own a Slice of Route 66 History – Prime Commercial Corner in Cuba, MO Step into opportunity with this 1920-built commercial building—just in time to open before Route 66’s 100th Anniversary! Located on a high-visibility corner lot in Cuba, this 900 sq ft space is ideal for a pizza shop, ice cream parlor, retail store, or office. Expansion is possible, and the location is unbeatable. Recent upgrades include a new mini-split HVAC system, updated gas and sewer lines, and floor rebuilt. Included security system and commercial refridgerator! Cuba draws heavy tourism year-round thanks to its Route 66 charm, river floats, and public art. With the Route 66 Centennial in 2026, this is a strategic time to buy, build, and be up and running before crowds hit. Just 1 hour from St. Louis and 20 minutes to Rolla, this commercial gem is a smart investment in both history and growth.