4531 Lisann St Tucked away on a tranquil cul-de-sac in the coveted Bay Ho neighborhood, this beautifully designed 2011-built residence offers impressive scale, versatility, and indoor-outdoor living, all framed by the peaceful greenery of a canyon backdrop. Soaring vaulted ceilings and abundant natural light enhance the expansive open floor plan, while rich wood and etched-glass entry doors, natural stone tile flooring, a striking tiled fireplace, and warm wood cabinetry add character throughout. At the heart of the home, the generous kitchen features granite countertops, a custom tile backsplash, stainless steel appliances, gas cooking, extensive cabinetry, and an oversized island with breakfast-bar seating and built-in wine storage. Two sliding doors extend the living space outdoors to a spacious backyard thoughtfully designed for relaxing, dining, and entertaining, complete with a covered patio and serene canyon surroundings. On the main level is the first primary suite with direct backyard access, a walk-in closet, and ensuite bath with custom-tiled walk-in shower, along with two additional generously sized bedrooms and an updated full bath. Upstairs, the remarkable secondary primary suite creates a private retreat and an exceptional level of flexibility. Vaulted ceilings, an ensuite bath with jetted tub and shower, abundant storage, and a private northwest-facing front balcony for enjoying colorful sunset skies are complemented by a spacious second living area with its own kitchenette plus central A/C and heating! This versatile space is ideal for extended family, guests, a private office, fitness or yoga studio, or simply an additional place to relax and unwind. Sliding doors open to an expansive 22.5' x 18' tiled rear balcony overlooking the backyard and peaceful canyon greenery, creating yet another inviting outdoor living space. With two primary suites, multiple living and entertaining areas, and a wonderfully private setting, this distinctive Bay Ho home offers a rare combination of space and versatility, just minutes from shopping, dining, convenient freeway access, and San Diego's world-renowned beaches and bays.