401 N Tigertail Rd Serenity patiently awaits at Villa Serenique, a truly one-of-one estate designed with deep reverence for organic materials, refined amenities, and understated sophistication. Located at 401 N Tigertail Road, just minutes from Brentwood Village, the home offers seamless access to L.A.'s premier dining, shopping, and hiking trails. Crafted over four years and thoughtfully designed with Tiffany Harris Design, Villa Serenique spans approximately 20, 000 square feet on over one acre, featuring nine bedrooms. The residence is wrapped inside and out in hand-chiseled Portuguese limestone, complemented by Roman plaster walls, travertine, and board-formed concrete creating a calm, timeless atmosphere rooted in nature. Beyond a gated entry, limestone steps lead to a grand double-height door opening into light-filled living and dining spaces divided by a limestone fireplace. Floor-to-ceiling glass frames hillside views and opens to expansive outdoor entertaining areas. The hosting level includes an open-air kitchen with gas and Argentinian-style grills, a pool and hot tub with sunken firepit seating, manicured lawns with citrus and olive trees, a private walnut-wrapped office, chef's kitchen with brass hood, industrial prep kitchen, two guest suites, laundry room, garage, and secured delivery cabinet. Upstairs, canyon and city views accompany three ensuite bedrooms, a lounge, and the primary retreat featuring a private balcony, silver travertine accents, dual spa-like bathrooms with heated floors, and custom walk-in closets.The lower level offers a world-class wellness and entertainment wing: an indoor-outdoor gym, Pilates studio, lap pool, cold plunge, infrared sauna, steam spa, car gallery with drive-in movie capability, and parking for 10 plus cars, soundproof theater, bar, wine cellar, and additional ensuite bedrooms. Below the home lies a private outdoor retreat with soccer field, a pickleball court, gardens, and an Italian-style dining terrace. Quiet yet central, Villa Serenique is a sanctuary that grounds, restores, and inspires an everyday retreat for mind, body, and spirit.