320 W Main St A rare opportunity to own a piece of Fredericksburg's history along iconic Main Street, The Itz Inn is a circa-1895 limestone landmark offering approximately 3, 798 SF. Currently operating as a hospitality property, it features four guest suites with private ensuite baths, additional commercial space, and four grandfathered lodging permits. Set across 0.48 acres, the property also offers something increasingly valuable downtown-substantial outdoor space, including a large rear yard, courtyard areas, and rear parking. Historic limestone and pioneer stone construction, exposed stone interiors, high ceilings, wood floors, and original architectural details preserve the distinctive character of the property. An expansive second-story covered gallery porch overlooking Main Street creates a memorable setting for guests, while the courtyards, mature trees, and historic cellar add another dimension to the property. Additional commercial space provides flexibility for a tasting room, retail concept, gallery, office, or expansion of the existing hospitality use. Positioned within walking distance of Fredericksburg's restaurants, wineries, shops, galleries, and attractions, The Itz Inn brings together established lodging, commercial versatility, generous grounds, and a premier Main Street location. Whether continued as a boutique hospitality property or reimagined as a distinctive mixed-use destination, this landmark presents a compelling opportunity to acquire a substantial downtown property with character, flexibility, and multiple avenues for future use.