25365 US HIGHWAY 281 S Exceptional opportunity to acquire 4.756 acres with both residential and commercial zoning on a frontage road in one of the fastest-growing corridors just minutes from San Antonio. With outstanding development potential, excellent visibility, and flexible zoning, this property is well-suited for a variety of commercial, mixed-use, or investment opportunities, subject to applicable zoning and permitting requirements. The value of the two existing homes are not being considered in the pricing and are being sold AS IS, with the primary value in the land. The level, wooded acreage features mature native trees and offers the flexibility to clear for development or incorporate the natural landscape into your project. Strategically located with convenient access to Loop 1604 and Highway 281, the property's frontage road location provides excellent accessibility and exposure, along with strong connectivity to major employment centers, established residential communities, and a growing customer base. Conveniently located near San Antonio's growing South Side employment corridor, offering easy access to major employers including Toyota Motor Manufacturing, HOLT CAT, TJ Maxx Distribution Center, pharmaceutical manufacturers, healthcare facilities, and numerous logistics and industrial employers-making this an ideal location for commuters.