22269 Avenue San Luis Contemporary Woodland Hills retreat with a resort-style pool and cabana! Tucked behind gates on a beautifully landscaped lot, this extensively renovated custom home blends upscale design with the ease of indoor-outdoor California living. Designed with high-end finishes throughout, including Roman Clay walls, soaring ceilings, and wide-plank White Oak floors, the home exudes a warm yet sophisticated aesthetic. The main level features a light-filled living room with a gas fireplace and an elegant dining area with a built-in bar. The gourmet kitchen is a chef's dream, complete with Thermador appliances, a walk-in pantry, and a center island with bar seating. Adjacent to the kitchen, there's a versatile media room, and an open-concept family room with a gas fireplace that flows seamlessly through sliding accordion doors to the backyard oasis. Outside, you'll find a sparkling pool and spa, al fresco dining, multiple lounge areas, and a cabana currently set up as a gym yet easily adaptable for an entertaining space. Upstairs, the luxurious primary suite boasts a gas fireplace, dual walk-in closets, a built-in vanity, and a private balcony. The spa-inspired bathroom offers a freestanding tub and refined finishes. All bedrooms are en-suite, with two conveniently located on the main level and the remainder upstairs, ensuring privacy and comfort for family and guests. Additional highlights include a temperature-controlled wine cellar, ample storage, a two-car garage, and a drive-in/drive-out motor court. Conveniently located near the 101 and moments from local amenities such as The Commons at Calabasas, The Village, Westfield Topanga, markets, and dining, this residence embodies upscale Woodland Hills living at its finest.