21305 Estero Preserve Run Tucked into the heart of Estero, this exceptional residence offers the rare combination of convenience and quiet serenity within a secure, gated natural gas community. Ideally positioned for easy access to major routes, yet peacefully set within a small enclave, this home delivers the best of both worlds. Set against a stunning natural backdrop, the rear yard overlooks a lush preserve where a branch of the Estero River gently winds through. Residents enjoy a charming wood walkway in the middle of the community that meanders through the Estero River Tributary Preserve-perfect for morning strolls or sunset unwinding. Inside, the thoughtfully designed floor plan features 3 Bedrooms plus a Den and 2 full Bathrooms, with upscale finishes throughout. Real wood flooring anchors the main living areas, complemented by crown molding and elegant tray ceilings in both the living room and primary suite. The kitchen is beautifully appointed with upgraded cabinetry, solid surface countertops, a gas cooktop, wall oven, and wall-mounted microwave, all paired with stainless steel appliances. Tile flooring enhances the bathrooms and laundry room, while upgraded carpeting adds comfort in the bedrooms. The primary suite is a private retreat, complete with dual walk-in closets outfitted with custom shelving and a spacious bathroom featuring dual sinks and an oversized shower. Both guest bedrooms also offer custom storage solutions, and plantation shutters throughout the home add timeless style and functionality. Step outside to a true SW Florida lifestyle experience. The expansive screened lanai showcases a gas-heated pool and spa, a built-in gas firepit, and a fully equipped outdoor kitchen with sink, refrigerator, gas grill, and wall-mounted TV-perfect for entertaining year-round. Roll-down electric storm shutters protect the lanai, with manual shutters for the remainder of the home. The garage is equally impressive, featuring an epoxy floor, custom cabinetry and storage systems, plus an additional sink for convenience. Recent updates provide peace of mind, including a new pool heater (March 2026), pool filter (2025), and a recently replaced HVAC blower motor (April 2026), with the system regularly serviced and a UV light replaced approximately four years ago. Located just minutes from shopping, dining, and entertainment at Coconut Point, Miromar Outlets, Gulf Coast Town Center & many other venues, as well as Florida Gulf Coast University, Lee Health Coconut Point, Estero Community Park, public golf courses, schools, and Southwest Florida International Airport. Beautiful Gulf beaches and scenic nature trails are also just a short drive away. All of this is complemented by low community fees that include gated security, lawn care, landscaping, and irrigation - making this home not only luxurious, but effortlessly livable.Set your viewing appointment today!