123 2nd Avenue S RARE OPPORTUNITY to establish a presence in Safety Harbor's Main Street Marketplace District, one of Pinellas County's most active and walkable small-city commercial corridors. Offered for lease is approximately +/-1, 460 SF of character-rich commercial space within a charming single-story stucco building dating back to the 1930s. The space features a versatile multi-room layout well suited for professional office, boutique retail, personal services, wellness, or creative studio use. The floor plan allows for a broad range of business configurations and includes a welcoming lobby or reception area, central open workspace, multiple private rooms or offices, a full bathroom, and a dedicated utility area. Recent capital improvements include a brand-new HVAC system installed in January 2026 and a roof replaced in 2013. On-site and street parking are available, and the property is located within the City of Safety Harbor's Community Redevelopment District, where MSM zoning supports a wide variety of commercial uses. The location offers exceptional visibility and steady pedestrian activity just off Main Street. The property sits directly behind the Safety Harbor Chamber of Commerce and across from Starbucks, one of downtown's strongest traffic generators. Surrounding businesses create a vibrant and established commercial environment, with nearby operators including Bar Fly Saltwater Grill, The Brinehouse, Cafe Vino Tinto, Sips Wine Bar, Bassano Cheesecake, and Athens Family Restaurant. The Safety Harbor Resort & Spa, a major regional draw and key driver of foot traffic, is only steps away at the top of Main Street. This is a rare chance to lease well-located commercial space in the heart of downtown Safety Harbor, in a proven walk-in-traffic location with limited available inventory of this character, size, and setting.