12200 Caisson Lane Experience the perfect blend of LUXURY, privacy, and NATURE in this beautifully UPDATED 4-bedroom, 3-bath POOL home with a 2-car garage, on a fenced 5-ACRE estate backing up to Six Mile Cypress Preserve. SEE VIDEO. Offering 2, 771 sq. ft. under air move-in-ready home combines peaceful living with a PRIME Fort Myers location near Daniels Parkway, I-75, near dining, shopping and RSW Airport. The backyard is a true RETREAT, highlighted by a expansive OUTDOOR LIVING space with 2141 sq ft of entertaining and recreative featuring an outdoor Kitchen, custom saltwater PebbleTec POOL (2022) with Hayward smart controls, automatic water fill, and a screened lanai. Step into the backyard to a FIRE pit, pond with water feature, PLAYGROUND, and endless nature to enjoy. Half the property is cleared and landscaped, while the wooded acreage features a private WALKING trail and natural buffer for ultimate seclusion. There is ample ROOM TO ADD a detached garage, workshop, barn, RV storage, guest house, or additional outbuildings while still maintaining privacy and natural beauty. RECENT UPGRADES: include a remodeled kitchen (2021), renovated primary bath (2023), updated hall bath and laundry room (2026), new flooring (2026), roof and gutters (2023), exterior paint (2023), main HVAC (2024), WHOLE house RO system and upstairs mini-split (2023). The grounds feature low-maintenance landscaping, new sidewalks, decorative rock beds, a Clusia privacy hedge, Shady Lady tree line, and an impressive collection of fruit and ornamental trees. With resort-style amenities, extensive updates, and unmatched privacy, this rare estate offers the very best of Southwest Florida living.